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1.
PLoS One ; 13(7): e0201133, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-30063762

RESUMO

The aim of this study was to evaluate the effects of oat beta-glucan supplementation on metabolic, physiological, immunological and nutritional variables in adult dogs. Fourteen dogs were fed a control diet or a diet supplemented with 1% beta-glucan during 71 days. Serum concentrations of glucose, total cholesterol and lipoprotein fractions, as well as plasma concentrations of peptide YY and ghrelin, were determined. In addition, coefficient of total tract apparent macronutrient digestibility (CTTAD), food intake and fecal output, score, and pH were evaluated. For evaluation of immunological variables, serum concentrations of interleukin-4 and interferon gamma were determined on days 0, 57 and 71, which corresponded to blood collection prior to beta-glucan supplementation, and at 7 and 14 days post first and second dose of vaccination (Pneumodog®, Merial, Campinas, Brazil), respectively. Animals fed the supplemented diet showed (P<0.05) lower serum concentrations of total cholesterol and low and very low density lipoproteins, lower coefficients of total tract apparent digestibility of dry matter, organic matter, mineral matter and ether extract, higher fecal output and lower fecal consistency, as well as a tendency (P = 0.07) of decreasing the coefficient of total tract apparent digestibility of crude protein. Moreover, the supplemented diet resulted in lower number of red blood cells, hematocrit percentage and hemoglobin concentration 21 days post-vaccination as well as lower serum concentration of interleukin-4 seven days post-vaccination (P<0.05). It is concluded that oat beta-glucan extract can be used as a dietary supplement for dogs at a dose of 10 g/kg of food, being effective in reducing blood concentrations of total cholesterol, LDL-c and VLDL-c as well as CTTAD of nutrients, demonstrating a potential to be used in the feeding of obese animals. In addition, by reducing the predominance of a Th2 response, oat beta-glucan can positively modulate the vaccine response of animals.


Assuntos
Avena , Suplementos Nutricionais , Cães , beta-Glucanas/administração & dosagem , Ração Animal , Fenômenos Fisiológicos da Nutrição Animal , Animais , Colesterol/sangue , Cães/metabolismo , Ingestão de Alimentos , Fezes , Interferon gama/sangue , Interleucina-4/sangue , Obesidade/dietoterapia , Obesidade/veterinária , Vacinação
2.
Ciênc. rural ; 46(8): 1456-1459, Aug. 2016. tab
Artigo em Inglês | LILACS | ID: lil-784198

RESUMO

ABSTRACT: This study aimed to evaluate the inclusion of Yucca schidigera extract and zeolite (Clinoptilolite) added to the diets for dogs and its effect on apparent digestibility coefficients (ADC) of diet components (dry matter, organic matter, crude protein, acid hydrolyzed fat, and energy) and urinary pH. Twenty-one adult Beagles, males and females, body weight mean of 12.5±1.5kg and four and a half years old, distributed in a completely randomized design with seven replicates per treatment within three experimental treatments: control (no addition of Yucca schidigera and zeolite), Yucca schidigera (375ppm) and zeolite (1%), administered in the encapsulated form of the supplement. The ADC of diet components and urinary pH were not affected by the inclusion of additives (P>0.05), except the ADC acid hydrolyzed fat showed reduction with Yucca schidigera supplementation compared to the other treatments (P<0.05). The addition of 375ppm of Yucca schidigera extract reduced the digestibility of dietary fat by dogs and both Yucca schidigera extract and zeolite did not affect the urinary pH of dogs.


RESUMO: O objetivo deste trabalho foi avaliar a inclusão do extrato de Yucca schidigera e da zeólita (Clinoptilolita) nas dietas para cães e seus efeitos sobre os coeficientes de digestibilidade aparente (CDA) dos componentes da dieta (matéria seca, matéria orgânica, proteína bruta, extrato etéreo em hidrólise ácida e energia) e no pH urinário. Foram utilizados 21 cães Beagles, machos e fêmeas, com peso médio de 12,5±1,5kg e quatro anos e meio de idade, distribuídos em delineamento inteiramente casualizado com sete repetições para cada um dos três tratamentos experimentais: controle (sem adição de Yucca schidigera e zeólita), Yucca schidigera (375ppm) e zeólita (1%), administrados na forma de suplemento encapsulado. Os CDA dos componentes da dieta e o pH urinário não foram afetados pela inclusão dos aditivos (P>0,05), exceto o CDA do extrato etéreo em hidrólise ácida, que reduziu com a suplementação de Yucca schidigera em comparação aos demais tratamentos (P<0,05). A adição de 375ppm de extrato de Yucca schidigera reduziu a digestibilidade da gordura dietética pelos cães e tanto a adição de Yucca schidigera como a de zeólita não alteraram o pH urinário.

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